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    Phase separation by fusion protein FC reveals new mechanism for tumor development in rare cancer

    2 days ago

    Dynamic remodeling of the endomembrane system is a core biological process essential for maintaining cellular compartmentalization and homeostasis. Proteins enriched in intrinsically disordered regions (IDRs) can drive membrane curvature formation in artificial vesicles through liquid-liquid phase separation (LLPS); however, direct evidence for LLPS-mediated endomembrane remodeling in living cells has been lacking.
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